Why simian crease

In: Kliegman RM, St. Nelson Textbook of Pediatrics. Reviewed By: Neil K. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.

Any duplication or distribution of the information contained herein is strictly prohibited. Browse A-Z Search. Browse A-Z. Pregnancy Smartsite TM. Transverse palmar crease; Palmar crease; Simian crease. There are typically two creases in the palm, but in some people, only one crease is present. A single palmar crease occurs in about 1 out of 30 people, but is also frequently associated with other conditions such as Down syndrome, Aarskog syndrome or fetal alcohol syndrome.

Distinct lines that form creases appear on the palms of the hands and soles of the feet. The palm has 3 of these creases in most cases. But sometimes, the creases join to form just one. Palmar creases develop while a baby is growing in the womb, most often by the 12th week of gestation.

A single palmar crease appears in about 1 out of 30 people. Males are twice as likely as females to have this condition.

Some single palmar creases may indicate problems with development and be linked with certain disorders. Having a single palmar crease is often normal. However, it may also be associated with various conditions that affect a person's mental and physical growth, including:. An infant with a single palmar crease may have other symptoms and signs that, when taken together, define a specific syndrome or condition.

Diagnosis of that condition is based on a family history, medical history, and complete physical exam. The study was performed per under the Helsinki Declaration , revised in It was a descriptive cross-sectional study. The aims and objectives of the study were explicitly explained to the participants before the commencement of the study. All participants voluntarily gave written informed consent to participate in the study.

The study was anonymous. A paper-and-pencil based method of filling questionnaires was utilized. All questionnaires were distributed evenly among first-year students through the final 4 th year on the university campus. The study was made between May and September The SRQ was developed and validated for international use. Compared to other scales for analysis of depression, the SRQ- 20 has better validity and is widely used to assess depression among University students [ 18 , 19 ]. Rosenberg Self-esteem Scale [ 20 ] was used to collect the scores associated with self-esteem.

The reliability and validity of the Rosenberg Self-esteem Scale have been well-demonstrated [ 21 , 22 ]. A p-value less than 0. Of 45 men, 22 were with simian crease and 23 were without it. Of 32 women, 16 were with the simian crease and 16 were not with the simian crease.

There were no simian crease statusrelated statistically significant differences in selfesteem scores in the total sample, in male and in female subjects Table 1. But, there was a simian crease status-related the statistically significant difference in the depression scores in only female subjects, not in the total sample and male subjects. However, single palmar creases can be associated with Down's syndrome and other genetic disorders, or with fetal alcohol syndrome.

Clinicians, anthropologists, and palmists were interested in the simian crease of the palm for hundreds of years.