Which hormone promotes rbc production

Learn more about our commitment to Global Medical Knowledge. This site complies with the HONcode standard for trustworthy health information: verify here. Common Health Topics. Videos Figures Images Quizzes Symptoms. Courtesy of. Approach to the Patient With Anemia. Test your knowledge. Nausea and vomiting are common adverse effects of either the cancer itself or of the treatment for cancer. A needle is used for drawing blood from a vein on your arm.

The test results may vary based on your age, sex, health status, and even the method used for the test. Your healthcare provider will discuss your results with you. Too little erythropoietin could be due to anaemia low red blood cells , especially anaemia due to kidney disease.

Increased levels of erythropoietin might be due to a condition called polycythaemia too many red blood cells or it could be evidence of a kidney tumour. Raised levels of Erythropoietin in athletes indicate erythropoietin abuse doping. EPO doping can boost the number of red blood cells and there by increased availability of oxygen to the muscles.

This can help the athlete with increased performance ability and endurance. Blood doping is illegal especially in professional sports. Professional athletes are asked to take this test to find out if they are violating the anti-doping law. About Contact Events News. Search Search. Erythopoietin is a protein hormone essential to production of red blood cells erythrocytes , which themselves deliver oxygen to all tissues in the body.

This hormone is synthesized in the kidney and its secretion is regulated by the amount of oxygen delivered to that organ. Erythropoietin was one of the first drugs produced through recombinant DNA technology and is widely used in conditions where red blood cell production is deficient.

In the fetus, it is synthesized in the liver, but production later switches almost exclusively to the kidney. Within the kidney, erythropoietin is produced by interstitial fibroblast-like cells that surround the renal tubules.

When blood oxygen concentration is normal normoxia , synthesis of erythropoietin occurs in scattered cells located predominantly in the inner cortex, but under conditions when blood oxygen is deficient hypoxia , interstitial cells within almost all zones of the kidney begin to produce the hormone.

This is an interesting concept - increased production of erythropoietin is due to an increase in the number of cells that produce it rather than an increase in the level of synthesis by particular endocrine cells. The red blood cells undergo 4 cell divisions in bone marrow before reaching their maturation. Erythropoietin is a red blood cell growth control hormone produced in the kidney.